Bristol-Myers Squibb to Present on Success of High Throughput Kinetic-Read Assays at GTCbio’s 2nd Assay Development & High Throughput Screening Conference (May 31-June 1, Boston, MA)
(PRLEAP.COM) Kingsley Appiah, Research Scientist in Lead Discovery at Bristol-Myers Squibb in Wallingford, Connecticut will present on “High Throughput Kinetic-Read Assays: Delivering Significantly Improved Assay Performance” at GTCbio’s 2nd Assay Development & High Throughput Screening Conference on May 31-June 1 in Boston, MA.
The advantages to reading an assay in kinetic mode rather than with a single endpoint read are numerous. It makes it possible to work within the initial reaction rate with very low substrate turnover. It enables the use of assays with very low signal and short linearity of reaction progress curves for hit identification. Also, it dramatically reduces physical interference from compounds in the screening collection. Historically, it has been very difficult to run these assays in HTS labs due to long read times and issues of data management for multiple reads. We have leveraged technology to make kinetic read for HTS a routine process. We will present how this has been achieved at BMS and give examples which clearly demonstrate the advantages of kinetic-mode screening.
GTCbio’s 2nd Assay Development & High Throughput Screening Conference on May 31-June 1 will take place at the Omni Parker House in downtown Boston, MA. The meeting will be held concurrently with GTCbio’s 2nd Protein Kinases in Drug Discovery Conference.
For more information including a detailed agenda, exhibitor opportunities and registration information visit http://www.gtcbio.com/conference/conferenceDetails.aspx?id=94
ABOUT GTCbio
GTCbio organizes conferences specifically for the biomedical and biopharmaceutical industries. Our goal is to facilitate the exchange of biopharmaceutical and biomedical intelligence between industry leaders, academic and government organizations, and the financial community.
GTCbio is a subsidiary of Global Technology Community, LLC, a privately held company founded in 2002.
Contact: GTCBIO (626) 256-6405, (626) 256-6460 fax, raniah@gtcbio.com
The advantages to reading an assay in kinetic mode rather than with a single endpoint read are numerous. It makes it possible to work within the initial reaction rate with very low substrate turnover. It enables the use of assays with very low signal and short linearity of reaction progress curves for hit identification. Also, it dramatically reduces physical interference from compounds in the screening collection. Historically, it has been very difficult to run these assays in HTS labs due to long read times and issues of data management for multiple reads. We have leveraged technology to make kinetic read for HTS a routine process. We will present how this has been achieved at BMS and give examples which clearly demonstrate the advantages of kinetic-mode screening.
GTCbio’s 2nd Assay Development & High Throughput Screening Conference on May 31-June 1 will take place at the Omni Parker House in downtown Boston, MA. The meeting will be held concurrently with GTCbio’s 2nd Protein Kinases in Drug Discovery Conference.
For more information including a detailed agenda, exhibitor opportunities and registration information visit http://www.gtcbio.com/conference/conferenceDetails.aspx?id=94
ABOUT GTCbio
GTCbio organizes conferences specifically for the biomedical and biopharmaceutical industries. Our goal is to facilitate the exchange of biopharmaceutical and biomedical intelligence between industry leaders, academic and government organizations, and the financial community.
GTCbio is a subsidiary of Global Technology Community, LLC, a privately held company founded in 2002.
Contact: GTCBIO (626) 256-6405, (626) 256-6460 fax, raniah@gtcbio.com
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Contact Information
Rania Hafez
GTCbio
Email GTCbio
626-256-6405